VERDANT NATURE

+ SNEDDS Technology ™

For more efficacious consumer products

Verdant nature and Molecular health logo

BIOAVAILABILITY MATTERS FOR HEALTH
AND TECHNOLOGY

Verdant Nature & SNEDDS Technology

As consumer interest in health supplements and nutrition continues to increase, efficacy and potency matters more than ever before. That’s where SNEDDS™ technology (Self Nano Emulsifying Dietary Delivery System) comes in. Considered to be the fuel that lights the fire to your active ingredients, SNEDDS Technology enhances their power making them more bioavailable and effective. With over 70 years of combined experience encompassing formulation, global sourcing, manufacturing, marketing, and distribution - Molecular Health Technologies offers you the most advanced, industry-leading technologies to help your brand stand out in a highly competitive industry.

WHAT

Molecular Health Technologies in partnership with Verdant Nature is offering you continued value, competitive advantage in the marketplace, and a better ROI with our current line of ingredients. Lastly, we can save you time/money by developing custom ingredients wrapped up in our SNEDDS™ technology for more efficacious consumer products.

HOW

Our SNEDDS™ technology greatly enhances solubility, permeability, avoidance of degradation in the liver, delivering the active in a homogenous state directly into the lymphatics and bioavailability – what we prefer to refer to as bioaccessibility.

WHY

Enabling consumers to gain the total benefits they are seeking by avoiding degradation of the active compound through first-pass metabolism in the liver. We change the supplement experience by increasing absorption and permeating the active compound directly into the cells confirmed through PAMPA studies.

SNEDDS™

LITERATURE SUPPORT

Verdant Nature & SNEDDS Technology

A FEW EXAMPLES IN LITERATURE DEMONSTRATING HOW IMPORTANT SNEDD’S INFUSION INTO COMMON MICROBIOLOGICAL COMPOUNDS USED IN CONSUMER MANUFACTURING PRODUCTS:

1. Thymoquinone “Thymoquinone is a poorly water soluble bioactive compound which shows poor oral bioavailability upon oral administration.” Enhanced oral bioavailability and hepatoprotective activity of thymoquinone in the form of phospholipid nano-constructs, C. Rathore, 2020 Expert Opinion on Drug Delivery, 17:2, 237-253

 

2. Berberine – “Studies have shown that the intestinal absorption efficiency of berberine is extremely low and the absolute bioavailability of berberine is as low as 0.68%”. Bioavailability study of berberine and the enhancing effects of TPGS on intestinal absorption in rats. Chen W., AAPS PharmSciTech. 2011;12:705–711.

 

3. Resveratrol – “Extensive metabolism in the intestine and liver results in an oral resveratrol bioavailability considerably less than 1%.” Bioavailability of resveratrol, Thomas Walle, Ann N Y Acad Sci. 2011 Jan;1215:9-15.

 

ADDITIONALLY, EACH OF OUR SNEDDS™ INGREDIENTS HAS COMPLETED SUPPORTIVE PAMPA (PARALLEL ARTIFICIAL MEMBRANE PERMEABILITY ASSAY) STUDIES (SEE ATTACHED) TO PROVE THEY HAVE SUBSTANTIALLY SIGNIFICANT IMPROVEMENTS IN DISSOLUTION, PERMEABILITY, PASSIVE DIFFUSION, AND AVOIDANCE OF LIVER DEGRADATION COMPARED TO STANDARDS. THIS IS ESSENTIAL FOR MAKING YOUR PRODUCTS MORE EFFECTIVE AND EFFICACIOUS RESULTING IN BETTER CONSUMER OUTCOMES AND ACCEPTANCE WHILE BEING MORE COST-EFFECTIVE.